Let's do some math ..  Rounding examples of 7 random hypothetical purchases:
  Case Tag  
Price  
Sales  
Tax %  
Raw Total  
Incl. Sales Tax  
Rounded  
to Penny  
Rounded  
to Nickel  
Rounded  
to Dime  
  Purchase #1 $20.72   4.134%   $21.5766   $21.58   $21.60   $21.60  
  Purchase #2 $95.30   4.832%   $99.9049   $99.90   $99.90   $99.90  
  Purchase #3 $135.52   9.360%   $148.2047   $148.20   $148.20   $148.20  
  Purchase #4 $132.82   4.678%   $139.0333   $139.03   $139.05   $139.00  
  Purchase #5 $80.81   11.653%   $90.2268   $90.23   $90.25   $90.20  
  Purchase #6 $68.86   12.708%   $77.6107   $77.61   $77.60   $77.60  
  Purchase #7 $64.39   10.720%   $71.2926   $71.29   $71.30   $71.30  
  7 purchase totals = $598.42       $647.8496   $647.84   $647.90   $647.80