Let's do some math ..  Rounding examples of 7 random hypothetical purchases:
  Case Tag  
Price  
Sales  
Tax %  
Raw Total  
Incl. Sales Tax  
Rounded  
to Penny  
Rounded  
to Nickel  
Rounded  
to Dime  
  Purchase #1 $21.28   3.622%   $22.0508   $22.05   $22.05   $22.10  
  Purchase #2 $105.34   5.569%   $111.2064   $111.21   $111.20   $111.20  
  Purchase #3 $111.51   3.475%   $115.385   $115.39   $115.40   $115.40  
  Purchase #4 $110.39   12.257%   $123.9205   $123.92   $123.90   $123.90  
  Purchase #5 $244.28   11.154%   $271.527   $271.53   $271.55   $271.50  
  Purchase #6 $224.95   13.662%   $255.6827   $255.68   $255.70   $255.70  
  Purchase #7 $133.83   8.333%   $144.9821   $144.98   $145.00   $145.00  
  7 purchase totals = $951.58       $1,044.7545   $1,044.76   $1,044.80   $1,044.80