Let's do some math ..  Rounding examples of 7 random hypothetical purchases:
  Case Tag  
Price  
Sales  
Tax %  
Raw Total  
Incl. Sales Tax  
Rounded  
to Penny  
Rounded  
to Nickel  
Rounded  
to Dime  
  Purchase #1 $19.85   10.639%   $21.9618   $21.96   $21.95   $22.00  
  Purchase #2 $77.43   3.321%   $80.0015   $80.00   $80.00   $80.00  
  Purchase #3 $217.51   11.841%   $243.2654   $243.27   $243.25   $243.30  
  Purchase #4 $13.76   5.324%   $14.4926   $14.49   $14.50   $14.50  
  Purchase #5 $225.65   10.243%   $248.7633   $248.76   $248.75   $248.80  
  Purchase #6 $27.98   5.298%   $29.4624   $29.46   $29.45   $29.50  
  Purchase #7 $128.68   4.809%   $134.8682   $134.87   $134.85   $134.90  
  7 purchase totals = $710.86       $772.8152   $772.81   $772.75   $773.00