Let's do some math ..  Rounding examples of 7 random hypothetical purchases:
  Case Tag  
Price  
Sales  
Tax %  
Raw Total  
Incl. Sales Tax  
Rounded  
to Penny  
Rounded  
to Nickel  
Rounded  
to Dime  
  Purchase #1 $247.63   13.733%   $281.637   $281.64   $281.65   $281.60  
  Purchase #2 $231.84   5.784%   $245.2496   $245.25   $245.25   $245.20  
  Purchase #3 $204.57   3.565%   $211.8629   $211.86   $211.85   $211.90  
  Purchase #4 $43.62   4.129%   $45.4211   $45.42   $45.40   $45.40  
  Purchase #5 $75.50   3.207%   $77.9213   $77.92   $77.90   $77.90  
  Purchase #6 $134.30   3.576%   $139.1026   $139.10   $139.10   $139.10  
  Purchase #7 $197.58   11.304%   $219.9144   $219.91   $219.90   $219.90  
  7 purchase totals = $1,135.04       $1,221.1089   $1,221.10   $1,221.05   $1,221.00