Let's do some math ..  Rounding examples of 7 random hypothetical purchases:
  Case Tag  
Price  
Sales  
Tax %  
Raw Total  
Incl. Sales Tax  
Rounded  
to Penny  
Rounded  
to Nickel  
Rounded  
to Dime  
  Purchase #1 $20.68   6.373%   $21.9979   $22.00   $22.00   $22.00  
  Purchase #2 $198.41   9.540%   $217.3383   $217.34   $217.35   $217.30  
  Purchase #3 $71.28   4.508%   $74.4933   $74.49   $74.50   $74.50  
  Purchase #4 $32.49   5.211%   $34.1831   $34.18   $34.20   $34.20  
  Purchase #5 $66.85   6.584%   $71.2514   $71.25   $71.25   $71.30  
  Purchase #6 $18.26   8.720%   $19.8523   $19.85   $19.85   $19.90  
  Purchase #7 $182.73   12.709%   $205.9532   $205.95   $205.95   $206.00  
  7 purchase totals = $590.70       $645.0695   $645.06   $645.10   $645.20