Let's do some math ..  Rounding examples of 7 random hypothetical purchases:
  Case Tag  
Price  
Sales  
Tax %  
Raw Total  
Incl. Sales Tax  
Rounded  
to Penny  
Rounded  
to Nickel  
Rounded  
to Dime  
  Purchase #1 $21.26   3.704%   $22.0475   $22.05   $22.05   $22.00  
  Purchase #2 $164.74   10.801%   $182.5336   $182.53   $182.55   $182.50  
  Purchase #3 $176.57   7.778%   $190.3036   $190.30   $190.30   $190.30  
  Purchase #4 $13.95   12.792%   $15.7345   $15.73   $15.75   $15.70  
  Purchase #5 $86.90   5.542%   $91.716   $91.72   $91.70   $91.70  
  Purchase #6 $71.65   8.355%   $77.6364   $77.64   $77.65   $77.60  
  Purchase #7 $192.28   4.440%   $200.8172   $200.82   $200.80   $200.80  
  7 purchase totals = $727.35       $780.7888   $780.79   $780.80   $780.60