Let's do some math ..  Rounding examples of 7 random hypothetical purchases:
  Case Tag  
Price  
Sales  
Tax %  
Raw Total  
Incl. Sales Tax  
Rounded  
to Penny  
Rounded  
to Nickel  
Rounded  
to Dime  
  Purchase #1 $21.27   3.161%   $21.9423   $21.94   $21.95   $21.90  
  Purchase #2 $67.97   6.253%   $72.2202   $72.22   $72.20   $72.20  
  Purchase #3 $235.58   10.666%   $260.707   $260.71   $260.70   $260.70  
  Purchase #4 $17.79   12.418%   $19.9992   $20.00   $20.00   $20.00  
  Purchase #5 $54.57   8.410%   $59.1593   $59.16   $59.15   $59.20  
  Purchase #6 $190.40   4.267%   $198.5244   $198.52   $198.50   $198.50  
  Purchase #7 $127.43   12.847%   $143.8009   $143.80   $143.80   $143.80  
  7 purchase totals = $715.01       $776.3533   $776.35   $776.30   $776.30