Let's do some math ..  Rounding examples of 7 random hypothetical purchases:
  Case Tag  
Price  
Sales  
Tax %  
Raw Total  
Incl. Sales Tax  
Rounded  
to Penny  
Rounded  
to Nickel  
Rounded  
to Dime  
  Purchase #1 $48.25   4.582%   $50.4608   $50.46   $50.45   $50.50  
  Purchase #2 $21.29   9.421%   $23.2957   $23.30   $23.30   $23.30  
  Purchase #3 $235.35   6.304%   $250.1865   $250.19   $250.20   $250.20  
  Purchase #4 $247.75   12.151%   $277.8541   $277.85   $277.85   $277.90  
  Purchase #5 $17.60   13.692%   $20.0098   $20.01   $20.00   $20.00  
  Purchase #6 $195.66   12.196%   $219.5227   $219.52   $219.50   $219.50  
  Purchase #7 $223.99   8.489%   $243.0045   $243.00   $243.00   $243.00  
  7 purchase totals = $989.89       $1,084.3341   $1,084.33   $1,084.30   $1,084.40