Let's do some math ..  Rounding examples of 7 random hypothetical purchases:
  Case Tag  
Price  
Sales  
Tax %  
Raw Total  
Incl. Sales Tax  
Rounded  
to Penny  
Rounded  
to Nickel  
Rounded  
to Dime  
  Purchase #1 $220.75   11.724%   $246.6307   $246.63   $246.65   $246.60  
  Purchase #2 $168.37   4.331%   $175.6621   $175.66   $175.65   $175.70  
  Purchase #3 $44.25   5.430%   $46.6528   $46.65   $46.65   $46.70  
  Purchase #4 $60.62   13.529%   $68.8213   $68.82   $68.80   $68.80  
  Purchase #5 $40.53   3.430%   $41.9202   $41.92   $41.90   $41.90  
  Purchase #6 $42.34   12.689%   $47.7125   $47.71   $47.70   $47.70  
  Purchase #7 $16.38   9.511%   $17.9379   $17.94   $17.95   $17.90  
  7 purchase totals = $593.24       $645.3375   $645.33   $645.30   $645.30