Let's do some math ..  Rounding examples of 7 random hypothetical purchases:
  Case Tag  
Price  
Sales  
Tax %  
Raw Total  
Incl. Sales Tax  
Rounded  
to Penny  
Rounded  
to Nickel  
Rounded  
to Dime  
  Purchase #1 $170.82   4.251%   $178.0816   $178.08   $178.10   $178.10  
  Purchase #2 $205.46   8.768%   $223.4747   $223.47   $223.45   $223.50  
  Purchase #3 $242.66   3.235%   $250.5101   $250.51   $250.50   $250.50  
  Purchase #4 $245.71   13.677%   $279.3158   $279.32   $279.30   $279.30  
  Purchase #5 $154.33   5.308%   $162.5218   $162.52   $162.50   $162.50  
  Purchase #6 $229.79   5.685%   $242.8536   $242.85   $242.85   $242.90  
  Purchase #7 $146.95   11.830%   $164.3342   $164.33   $164.35   $164.30  
  7 purchase totals = $1,395.72       $1,501.0918   $1,501.08   $1,501.05   $1,501.10