Let's do some math ..  Rounding examples of 7 random hypothetical purchases:
  Case Tag  
Price  
Sales  
Tax %  
Raw Total  
Incl. Sales Tax  
Rounded  
to Penny  
Rounded  
to Nickel  
Rounded  
to Dime  
  Purchase #1 $159.77   4.333%   $166.6928   $166.69   $166.70   $166.70  
  Purchase #2 $40.64   13.136%   $45.9785   $45.98   $46.00   $46.00  
  Purchase #3 $239.83   5.462%   $252.9295   $252.93   $252.95   $252.90  
  Purchase #4 $158.61   8.197%   $171.6113   $171.61   $171.60   $171.60  
  Purchase #5 $44.41   3.628%   $46.0212   $46.02   $46.00   $46.00  
  Purchase #6 $39.42   8.408%   $42.7344   $42.73   $42.75   $42.70  
  Purchase #7 $174.97   11.720%   $195.4765   $195.48   $195.50   $195.50  
  7 purchase totals = $857.65       $921.4442   $921.44   $921.50   $921.40