Let's do some math ..  Rounding examples of 7 random hypothetical purchases:
  Case Tag  
Price  
Sales  
Tax %  
Raw Total  
Incl. Sales Tax  
Rounded  
to Penny  
Rounded  
to Nickel  
Rounded  
to Dime  
  Purchase #1 $21.41   5.243%   $22.5325   $22.53   $22.55   $22.50  
  Purchase #2 $202.51   9.747%   $222.2486   $222.25   $222.25   $222.20  
  Purchase #3 $95.95   9.461%   $105.0278   $105.03   $105.05   $105.00  
  Purchase #4 $141.55   12.389%   $159.0866   $159.09   $159.10   $159.10  
  Purchase #5 $91.98   6.187%   $97.6708   $97.67   $97.65   $97.70  
  Purchase #6 $177.81   3.121%   $183.3595   $183.36   $183.35   $183.40  
  Purchase #7 $106.58   4.147%   $110.9999   $111.00   $111.00   $111.00  
  7 purchase totals = $837.79       $900.9257   $900.93   $900.95   $900.90