Let's do some math ..  Rounding examples of 7 random hypothetical purchases:
  Case Tag  
Price  
Sales  
Tax %  
Raw Total  
Incl. Sales Tax  
Rounded  
to Penny  
Rounded  
to Nickel  
Rounded  
to Dime  
  Purchase #1 $38.53   13.695%   $43.8067   $43.81   $43.80   $43.80  
  Purchase #2 $61.97   5.194%   $65.1887   $65.19   $65.20   $65.20  
  Purchase #3 $43.81   10.541%   $48.428   $48.43   $48.45   $48.40  
  Purchase #4 $89.52   13.648%   $101.7377   $101.74   $101.75   $101.70  
  Purchase #5 $126.77   10.537%   $140.1278   $140.13   $140.15   $140.10  
  Purchase #6 $129.74   12.810%   $146.3597   $146.36   $146.35   $146.40  
  Purchase #7 $90.49   10.479%   $99.9724   $99.97   $99.95   $100.00  
  7 purchase totals = $580.83       $645.6210   $645.63   $645.65   $645.60