Let's do some math ..  Rounding examples of 7 random hypothetical purchases:
  Case Tag  
Price  
Sales  
Tax %  
Raw Total  
Incl. Sales Tax  
Rounded  
to Penny  
Rounded  
to Nickel  
Rounded  
to Dime  
  Purchase #1 $20.61   4.150%   $21.4653   $21.47   $21.45   $21.50  
  Purchase #2 $74.38   7.850%   $80.2188   $80.22   $80.20   $80.20  
  Purchase #3 $71.73   9.349%   $78.436   $78.44   $78.45   $78.40  
  Purchase #4 $36.42   3.663%   $37.7541   $37.75   $37.75   $37.80  
  Purchase #5 $9.45   6.155%   $10.0316   $10.03   $10.05   $10.00  
  Purchase #6 $131.32   7.684%   $141.4106   $141.41   $141.40   $141.40  
  Purchase #7 $238.51   6.745%   $254.5975   $254.60   $254.60   $254.60  
  7 purchase totals = $582.42       $623.9139   $623.92   $623.90   $623.90