Let's do some math ..  Rounding examples of 7 random hypothetical purchases:
  Case Tag  
Price  
Sales  
Tax %  
Raw Total  
Incl. Sales Tax  
Rounded  
to Penny  
Rounded  
to Nickel  
Rounded  
to Dime  
  Purchase #1 $152.50   4.563%   $159.4586   $159.46   $159.45   $159.50  
  Purchase #2 $10.63   5.623%   $11.2277   $11.23   $11.25   $11.20  
  Purchase #3 $56.78   11.219%   $63.1501   $63.15   $63.15   $63.20  
  Purchase #4 $246.84   10.874%   $273.6814   $273.68   $273.70   $273.70  
  Purchase #5 $9.59   9.790%   $10.5289   $10.53   $10.55   $10.50  
  Purchase #6 $20.39   7.364%   $21.8915   $21.89   $21.90   $21.90  
  Purchase #7 $101.71   4.709%   $106.4995   $106.50   $106.50   $106.50  
  7 purchase totals = $598.44       $646.4377   $646.44   $646.50   $646.50