Let's do some math ..  Rounding examples of 7 random hypothetical purchases:
  Case Tag  
Price  
Sales  
Tax %  
Raw Total  
Incl. Sales Tax  
Rounded  
to Penny  
Rounded  
to Nickel  
Rounded  
to Dime  
  Purchase #1 $21.54   5.846%   $22.7992   $22.80   $22.80   $22.80  
  Purchase #2 $119.98   8.195%   $129.8124   $129.81   $129.80   $129.80  
  Purchase #3 $70.63   13.504%   $80.1679   $80.17   $80.15   $80.20  
  Purchase #4 $63.99   3.245%   $66.0665   $66.07   $66.05   $66.10  
  Purchase #5 $70.65   7.724%   $76.107   $76.11   $76.10   $76.10  
  Purchase #6 $71.44   12.677%   $80.4964   $80.50   $80.50   $80.50  
  Purchase #7 $74.29   11.270%   $82.6625   $82.66   $82.65   $82.70  
  7 purchase totals = $492.52       $538.1119   $538.12   $538.05   $538.20