Let's do some math ..  Rounding examples of 7 random hypothetical purchases:
  Case Tag  
Price  
Sales  
Tax %  
Raw Total  
Incl. Sales Tax  
Rounded  
to Penny  
Rounded  
to Nickel  
Rounded  
to Dime  
  Purchase #1 $21.34   3.424%   $22.0707   $22.07   $22.05   $22.10  
  Purchase #2 $39.96   4.806%   $41.8805   $41.88   $41.90   $41.90  
  Purchase #3 $113.61   9.387%   $124.2746   $124.27   $124.25   $124.30  
  Purchase #4 $161.25   3.683%   $167.1888   $167.19   $167.20   $167.20  
  Purchase #5 $43.25   4.538%   $45.2127   $45.21   $45.20   $45.20  
  Purchase #6 $74.69   3.787%   $77.5185   $77.52   $77.50   $77.50  
  Purchase #7 $12.83   3.703%   $13.3051   $13.31   $13.30   $13.30  
  7 purchase totals = $466.93       $491.4509   $491.45   $491.40   $491.50