Let's do some math ..  Rounding examples of 7 random hypothetical purchases:
  Case Tag  
Price  
Sales  
Tax %  
Raw Total  
Incl. Sales Tax  
Rounded  
to Penny  
Rounded  
to Nickel  
Rounded  
to Dime  
  Purchase #1 $21.51   3.545%   $22.2725   $22.27   $22.25   $22.30  
  Purchase #2 $191.49   13.131%   $216.6346   $216.63   $216.65   $216.60  
  Purchase #3 $211.68   11.846%   $236.7556   $236.76   $236.75   $236.80  
  Purchase #4 $162.44   11.498%   $181.1174   $181.12   $181.10   $181.10  
  Purchase #5 $113.67   12.124%   $127.4514   $127.45   $127.45   $127.50  
  Purchase #6 $81.31   13.600%   $92.3682   $92.37   $92.35   $92.40  
  Purchase #7 $116.68   8.554%   $126.6608   $126.66   $126.65   $126.70  
  7 purchase totals = $898.78       $1,003.2605   $1,003.26   $1,003.20   $1,003.40