Let's do some math ..  Rounding examples of 7 random hypothetical purchases:
  Case Tag  
Price  
Sales  
Tax %  
Raw Total  
Incl. Sales Tax  
Rounded  
to Penny  
Rounded  
to Nickel  
Rounded  
to Dime  
  Purchase #1 $242.49   4.562%   $253.5524   $253.55   $253.55   $253.60  
  Purchase #2 $44.30   9.673%   $48.5851   $48.59   $48.60   $48.60  
  Purchase #3 $15.32   3.206%   $15.8112   $15.81   $15.80   $15.80  
  Purchase #4 $240.29   8.722%   $261.2481   $261.25   $261.25   $261.20  
  Purchase #5 $188.36   9.422%   $206.1073   $206.11   $206.10   $206.10  
  Purchase #6 $150.36   8.863%   $163.6864   $163.69   $163.70   $163.70  
  Purchase #7 $50.96   3.689%   $52.8399   $52.84   $52.85   $52.80  
  7 purchase totals = $932.08       $1,001.8304   $1,001.84   $1,001.85   $1,001.80